Application of Biotechnology in Health and Agriculture ( Human Insulin and Vaccine Production, Gene Therapy; Genetically Modified Organisms-Bt crops; Transgenic Animals; Biosafety issues-Biopiracy and Patents) NEET Questions

Application of Biotechnology in Health and Agriculture ( Human Insulin and Vaccine Production, Gene Therapy; Genetically Modified Organisms-Bt crops; Transgenic Animals; Biosafety issues-Biopiracy and Patents) MCQ Questions

1.
In which year did Eli Lilly company produce recombinant human insulin?
A.
2003
B.
1983
C.
1990
D.
1973
ANSWER :
B. 1983
2.
Insulin used by diabetic patients earlier was extracted from:
A.
Slaughtered cattle and pigs (pancreas)
B.
Goat liver
C.
Human cadavers
D.
Genetically modified yeast
ANSWER :
A. Slaughtered cattle and pigs (pancreas)
3.
Mature human insulin consists of:
A.
Four polypeptide chains held by hydrogen bonds
B.
Three polypeptide chains
C.
Two polypeptide chains (A and B) linked by disulphide bridges
D.
A single polypeptide chain
ANSWER :
C. Two polypeptide chains (A and B) linked by disulphide bridges
4.
In mammals, insulin is initially synthesised as a:
A.
Polypeptide with chain C only
B.
Pre-insulin only
C.
Mature insulin directly
D.
Pro-hormone (proinsulin) with an extra C-peptide
ANSWER :
D. Pro-hormone (proinsulin) with an extra C-peptide
5.
The C-peptide of proinsulin:
A.
Is the active part of insulin
B.
Binds to insulin receptors
C.
Forms part of mature insulin
D.
Is removed during maturation of proinsulin into insulin
ANSWER :
D. Is removed during maturation of proinsulin into insulin
6.
The main challenge faced in producing insulin using rDNA techniques was:
A.
Extracting DNA from pancreas
B.
Getting insulin assembled into a mature form
C.
Cloning the gene
D.
Killing the bacteria
ANSWER :
B. Getting insulin assembled into a mature form